Three Sisters Cafe

6360 Guilford Ave, Indianapolis, IN 46220 Directions
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100% of 19 customers recommended

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About this business

  • Cuisine
    Cafe, American, Vegetarian, Bakery, Continental
  • Meals
    Breakfast, Lunch, Dinner
  • Website
  • Price
  • Cuisine
    Cafe, American, Vegetarian, Bakery, Continental
  • Meals
    Breakfast, Lunch, Dinner
  • Show More
  • Attire
  • Alcohol
  • Parking
  • Delivery
  • Takeout
  • Reservations
  • Vegetarian Options
  • Good For Kids
  • Kids Menu
  • Vegan Options
  • Show Less



From Our Editors

Recently spotlighted by Metromix Indianapolis as one of the city's best options for vegetarians, 3 Sisters Cafe sates vores both carni- and herbi- with a menu of inventive dishes forged from fresh, local ingredients. Featured on the "Signature Sandwiches" episode of Food Network's Diners, Drive-ins and Dives, the D'nai sandwich soundtracks lunchtime masticators with Shakespearean soliloquies as they vanquish its midsection of slow-roasted ham and braised kale ($11). For breakfast, toast the wholesome marriage of lemon corncakes and fresh seasonal berries before ending it with a delectable digestive annulment ($8.50). Otherwise, demonstrate fungi fidelity with the vegan portobello burger for dinner ($8.50), or defy meal orthodoxy with a late-evening dollop of decadent vanilla-cream french toast ($5.25, breakfast served all day).

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