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Looking for a Botox Alternative? Here’s What Actually Works

BY: Colleen Loggins Loster | Mar 29, 2019

Yes, it's possible to treat wrinkles with a Botox alternative. Here's what you need to know. 

Older woman with wrinkles

According to the American Society of Plastic Surgeons, every year, more and more people are getting injectables to treat their wrinkles. The most popular of those injectables? Botox.

But what if you want to treat your wrinkles without Botox? Maybe you want to see what other injectables are out there. Maybe you would prefer a topical. Or maybe, you’ve reached the purchase limit on our Botox deals near you. Luckily, you can get a Botox alternative. Allow us to break down.

woman getting injected with a Botox alternative between her brows



When you want serious, immediately noticeable results in the fight against wrinkles, freezers are the way to go. And if you’re looking for the best Botox alternative, something that is very similar to Botox, you’ll want one of these other two botulinum toxin type A injectables.


Similarities to Botox

  • Paralyzes muscles in the forehead so they can't move
  • Lasts up to four months
  • Similar side effects and contraindications


  • Not FDA-approved to treat crow's-feet or forehead wrinkles. Some doctors go "off-label" and use Dysport on these areas anyway.
  • Measured differently. A forehead that needs 50 units of Dysport might only need 25 units of Botox.
  • Dysport has a tendency to spread, making it easier to tackle larger surfaces areas with less.

Shop Dysport deals


Similarities to Botox

  • Paralyzes muscles in the forehead so they can’t move
  • Very similar formula minus a few different proteins
  • Similar side effects and contraindications


  • Not FDA-approved to treat crow's-feet or forehead wrinkles. Some doctors go "off-label" and use Xeomin on these areas anyway.
  • Typically a bit cheaper than Botox
  • Lasts about three months

Shop Xeomin deals

Woman getting filler injected near her mouth



Technically, fillers aren’t Botox alternatives. Botox treats wrinkles on the forehead and around the eyes. Fillers treat wrinkles in other areas of the face, such as around the mouth. But fillers are actually better than Botox if you want to smooth your smile lines and chin wrinkles. They also last longer.

Hyaluronic Acid Fillers

These plump up the skin with hyaluronic acid, a substance that occurs naturally in the body. Options include Juvéderm, Restylane, and Belotero Balance.

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Other Fillers

Some fillers use microspheres and other substances to add structure back into the face and smooth wrinkles around the mouth and nose. These include Radiesse (CaHA microspheres in gel), Bellafill (PMMA microspheres in collagen solution), and Sculptra Aesthetic (poly-L-lactic acid).

Shop filler deals

woman getting a laser skin resurfacing treatment


Cosmetic Procedures

Various procedures performed at med spas and dermatologist offices can help improve wrinkles significantly. Keep in mind, though, that results aren’t immediate, and you’ll typically require multiple treatments.

Laser Skin Resurfacing

There are many different types of lasers, but three varieties are particularly effective when it comes to wrinkles: CO2 lasers, Erbium lasers, and fractional lasers. The most effective of these are ablative lasers—wounding lasers that remove thin layers of skin, forcing it to heal itself and kickstarting collagen production.

Results include smoother wrinkles and a more even skin tone, though you will likely experience a few weeks of downtime, after which results will start to appear.

Shop laser skin-resurfacing deals


Like lasers, microneedling devices injure the skin so it’s forced to heal itself and produce more collagen. Microneedling treatments are typically less invasive than laser treatments, however, and you’ll need a series of about 6–10 treatments to see smoother skin.

You may get even better results if you combine microneedling with platelet rich plasma (PRP) treatments, which use the platelets from your body to help encourage skin regeneration. PRP treatments are sometimes referred to by the trademarked name Vampire Facial.

Shop microneedling deals and PRP deals

Woman applying a topical wrinkle-fighting cream



Did you know that you can treat wrinkles with topicals? It’s true! Certain topical ingredients have been proven to help improve wrinkles, and they’re a great option if injectables and cosmetic procedures aren’t for you. Just know that It takes months to see any wrinkle-fighting results from topicals, and the results you do see are fairly subtle.


Retinoids—vitamin-A derivatives—are considered to be the gold-standard topical treatment for wrinkles. They smooth wrinkles by increasing collagen and elastin production and thickening the dermal layer.

Prescription-only retinoids (like Retin A and its generic form, tretinoin) contain retinoic acid.  Over-the-counter retinoids often contain another vitamin-A derivative called retinol. As our guide to retinoids points out, they’re biochemically the same, but it takes longer to see results with retinol.

Note: Many nonprescription “retinol” products contain pro-retinols, such as retinyl palmitate, retinyl acetate, and retinyl linoleate, which are most likely too weak to do anything. So if you go for an over-the-counter retinol, make sure it lists retinol as one of the ingredients.  

Vitamin C

Topical vitamin C can also help fight wrinkles, as it has been shown to increase collagen and elastin production. Vitamin C is most likely not as effective at fighting wrinkles as a retinoid, so if you’re only going to choose one, go with the retinoid.


OK, so sunscreen isn’t a topical Botox alternative that will get rid of wrinkles. But it is a topical treatment that will help prevent wrinkles. Plus, it’s 100% necessary if you decide to do any wrinkle-fighting cosmetic procedures or use wrinkle-fighting topicals, which tend to make the skin more vulnerable to the sun. You wouldn’t want to undo all your work, would you?

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