Sanctuary spa, Paoli

Clients will feel their stress melt away as soon as they step through the doors of Sanctuary Med Spa & Salon. The Tuscan-inspired decor is all about luxury, from the velvet settees and fireplace in the lounge area to the eight tastefully decorated private treatment rooms tucked behind sliding barn doors. There's even a private terrace garden and koi pond outside.

The luxury continues with a menu of beautifying med-spa services—most of which involve little to no downtime. Aestheticians rejuvenate skin with everything from custom clinical facials to Botox injections and nonsurgical face-lifts. Or clients can opt for one of the relaxing body treatments, whether a hot-stone massage or a Stress Less body polish.