Twentyone Cakes, Nixa

Named both for the bakery's 21 flavors and as a nod to the owners' son, who has Down syndrome—a disorder stemming from an extra copy of the 21st chromosome—TwentyOne Cakes crafts confections of every size within its sky-and-toffee-hued café. The lineup of seasonal flavors, such as german chocolate, gingerbread, and maple bacon, takes on colorful frosting and chatty personalities as it transforms into full cakes, three sizes of cupcakes, and bite-size cake balls. The eatery's brigade of tables mingles with a pair of comfy armchairs to give patrons respite during sugar comas, and free WiFi keeps brains busy in between sips of coffee or tea. As part of the company's mission to bring acceptance and awareness of individuals with Down syndrome, 10 percent of each purchase at TwentyOne Cakes goes to benefit Down Syndrome Group of the Ozarks.