Museum of Science and Industry, Tampa

Tampa's Museum of Science & Industry—also known as MOSI—has all the answers; even to questions you hadn't thought up yet. What would it be like to live on the moon? Head over to Mission: Moonbase for a detailed simulation. What did the night sky look like in the distant past and what will it look like in the future? The Saunders Planetarium can conjure the starscape of any era. These are just two of the museum's 450 hands-on activities, which also include The Amazing You—an interactive exhibit that explores the process of human development—and the BioWorks Butterfly Garden.

All of these activities feed into the nonprofit, community-based museum's mission of making science fun and accessible to curious citizens of all ages. It is home to a massive children's museum, a water treatment facility that doubles as an exhibit on marshy ecosystems, and an IMAX dome theater—the only one of its kind in Florida.