Mile 277 Tap & Grill, St. Louis

Like many clubs, Mile 277 Tap & Grill has a mascot. But unlike many clubs, it chose a mascot that was not the least bit cutesy—a custom-built motorcycle. That chopper now sits behind the main bar of the biker-themed restaurant, where roadhouse food meets nightclub vibes. It's not the only bike in the joint, either. Hand-painted motorcycle murals brighten the walls, and roped-off areas display motorcycles from local merchants. Even the 20 high-definition TVs probably flash a bike on their screens now and then.

Despite the hog-heavy environment, founder Keith Rhodes wasn't looking to run just another biker joint. He wanted to combine the gritty feel of a highway stop with the festivity of a DJ'ed party—hence, Mile 277 hosts live music and events most nights every week. Before the show, guests can peruse a menu of classic bar and comfort food, with some eclectic tweaks (salmon burgers, orzo pasta, and chimichangas to name a few). The eats and the drinks all follow the chopper theme. Beer is called "fuel," for example, and martinis are "mototinis," but neither are acceptable substitutes for engine oil.