Luna Derosa's chefs draw inspiration from a variety of cultures, but their emphasis remains on approachable comfort cuisine with a refined edge. Although the menu features numerous Italian staples—including iconic Sunday gravy with braised meatballs, sausage, and beef braciola in tomato sauce—it also incorporates a variety of Asian and American influences. Chefs add a piquant dose of trans-Atlantic flavor with spicy Thai chili sauces and sriracha-spiked sour cream. They also sear porterhouse steaks, new york strips, and filet mignon on the kitchen's flat-iron grill. The bartenders, meanwhile, mix innovative cocktails using sage, muddled jalapeños, or flavored vodkas, which they infuse in-house.
Illuminated columns dominate the split-level dining room, helping to gently light the space along with modern track lighting, chandeliers, and elegant wall sconces. The restaurant opens its outdoor patio during the warmer seasons so that diners can enjoy their meal beneath the stars, beside a smoldering fireplace, or in plain view of any attractive hot-air-balloon captains passing overhead.