Have tried everything but with very little relief. After reading about these Copper Compression Gloves I decided to try them. I have rheumatoid arthritis very badly in my right hand which is also my dominant hand. Took a couple of days to adjust to wearing them but has helped tremendously with the pain!! Was in to see my doctor this week and he was very interested in my gloves and asking lots of questions and very pleased with the results I'm having. Thinking about ordering an extra pair. I would definitely recommend for anyone with hand problems but especially arthritis!!