San Francisco Botox practitioners can effectively smooth skin with Botox for wrinkles, dry up armpits with Botox for sweating, and even quell sharp pain with Botox for headaches. The treatment is quite versatile. But what is Botox, exactly, and what is Botox made of? Botox is a prescription medication that is injected into muscles by trained medical practitioners. It contains tiny amounts of a highly purified botulinum toxin protein from the bacterium clostridium botulinum. So is Botox safe? Though Botox side effects can be serious and even life-threatening, the Mayo Clinic states that injections are generally considered safe when they are performed by an experienced doctor. Partly because of the number of Botox injections performed, America leads the world in the number of nonsurgical cosmetic procedures performed each year. Read more about Botox here.